Tom's Hardware found no significant difference between single-channel and dual-channel configurations in synthetic and game benchmarks (using a "modern" system setup). Generally speaking, dual channel configuration is a very minor upgrade, and without other system tweaks, the difference may not even be noticeable. While there is no reason not to use dual-channel over single-channel, where all other things are equal, the question often comes up whether it is advisable to add additional RAM if doing so will break dual-channel compatibility. Having more total RAM available is generally more beneficial than maintaining dual-channel configuration.
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